대한흉부영상의학회 Korean Society of Thoracic Radiology

Discussion

Diagnosis With Brief Discussion

Chief Complaint

Cough for 1 month, weight loss (8kg)

Definitive Diagnosis

Engraftment syndrome

Past History

Primary myelofibrosis

Reviewy

PERDS (peri-engraftment respiratory distress syndrome)
Occur during the engraftment of hematopoietic stem cells and neutrophil recovery
Diffuse capillary leak, cutaneous rash, and fever
Pathogenesis, not completely understood
Release of proinflammatory cytokines
Within 5 days of engraftment, or 7?21 days after transplant
Image finding
Thickening of the interlobular septa
Associated with bilateral ground-glass opacities
Perihilar or peribronchial consolidation
Pleural effusion
→ Indistinguishable from that of pulmonary edema

Absence of cardiac enlargement
Absence of other clinical findings of pulmonary edema
Presence of a skin rash and fever

Prognosis generally good
Spontaneously or respond promptly to steroid treatment

Keywords